Dumitru Arian

• Undergraduate Chemistry 2001-2007 (Moldova State University, Chisinau)

• PhD Chemistry 2007-2010, Prof. Dr. Andriy Mokhir (University of Heidelberg)

• Postdoctoral Fellow 2011-2013, Prof. Dr. Marc Greenberg (Johns Hopkins University, Baltimore)

• Research Assistant since 2013, Prof. Dr. Roland Krämer

Responsibilities:

• supervision of laboratory equipment
• conduct research projects
• mentor bachelor/master students
• organization of MC2 Practicum

Publications:

1. A Simple Method for Monitoring Protein-DNA Interactions. Fülöp, A.; Arian, D.; Lysenko, A.; Mokhir, A. Bioorg. Med. Chem. Lett. 2009, 19, 3104-3107.
2. A Nucleic Acid Dependent Chemical Photocatalysis in Live Human Cells. Arian, D.; Cló, E.; Gothelf, K.V.; Mokhir, A. Chem. Eur. J. 2010, 16, 288-295.
3. Single Molecule AFM Studies of Photosensitized Singlet Oxygen Behavior on a DNA Origami Template. Helmig, S.; Rotaru, A.; Arian, D.; Kovbasyuk, L.; Arnbjerg, J.; Ogilby, P.R.; Kjems, J.; Mokhir, A., Besenbacher, F.; Gothelf, K.V. ACS Nano 2010, 4, 7475-7480.
4. 1,9-Di(alkoxy)anthracene as a Singlet Oxygen-Sensitive Linker. Arian, D.; Kovbasyuk, L.; Mokhir, A. J. Am. Chem. Soc. 2011, 133, 3972-3980.
5. Control of the Photocatalytic Activity of Bimetallic Complexes of Pyropheophorbide-a by Nucleic Acids. Arian, D.; Kovbasyuk, L.; Mokhir, A. Inorg. Chem. 2011, 50, 12010-12017.
6. Irreversible Inhibition of DNA Polymerase β by Small-Molecule Mimics of a DNA Lesion. Arian, D.; Hedayati, M.; Zhou, H.; Bilis, Z.; Chen, K.; DeWeese, T. L.; Greenberg, M. M. J. Am. Chem. Soc. 2014, 136, 3176-3183.
7. A Chromogenic and Fluorogenic Peptide Substrate for the Highly Sensitive Detection of Proteases in Biological Matrices. Arian, D.; Harenberg, J.; Krämer, R. J. Med. Chem. 2016, 59(16), 7576-7583.